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The BeAT goes on: human milk maintains brown and beige adipose tissue in infants

Compared to most other, non-aquatic animals, we give birth to infants with relatively amounts of body fat. This has been hypothesized to explain why our infants can sustain a weight loss of 8-10% after birth while receiving immune factor rich colostrum. Infant body fat frequently increases across the first few months of life, and it is generally thought that this is in anticipation of nutritional stresses that may be associated with weaning and independent motor development (crawling, walking). However, baby fat is not all the same – babies actually have multiple different types of fat (also called adipose tissue). When it comes to BAT, BeAT, and babies, we actually know very little about the production and maintenance of BAT and BeAT (this is actually true for all ages). What can explain the differences seen in rates of BAT and BeAT decline in different infants based on the handful of studies? The answer may be BREAST MILK.

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Nothing beats MOM: changing donor milk microbiota using an infant’s mother’s milk

In the neonatal intensive care unit, human milk is preferred food for preterm and very preterm infants. For very premature infants (less than 30 weeks), it is well established that human milk reduces the risk of necrotizing enterocolitis (NEC), a bacterial infection of the intestines with devasting consequences, and is associated with improved growth, cognitive development, and survival compared to infants receiving formula. There’s just one problem: donor milk, used when an premature infant’s mother’s own milk (MOM) is not available, generally consists of pooled and pasteurized milk from several donors. Donor milk – the second best food for premature infants after milk from the infant’s own mother – is suddenly missing one OR MORE of the factors in human milk that is thought to protect against NEC and other gastrointestinal infections. But, what would happen if you incubated donor milk with unpasteurized milk, from the infant’s own mother?

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Milk remembers: Immune factors in milk “remember” childhood environments – repost from Biomarkers & Milk

It is well established that with very few exceptions, human milk is the preferred first food for infants. While the benefits of breastfeeding/receiving human milk are considerable and influence the development of multiple systems in the infant, perhaps the best known benefits of human milk are its immunoprotective properties. Worldwide, breastfeeding is associated with reduced risk of infectious diseases in infants, and these protections persist even in highly hygienic conditions such as the United States (Bartick & Reinhold 2010). Many immune factors are found in human milk, including immune cells, cytokines that regulate immune responses, and secretory Immunoglobulin-A (sIgA), perhaps the most common immunoprotein in human milk. It is well established that there is considerable variation in the immune factors in milk between individual mothers and between populations. It is also known that many of the immune factors in milk are highly responsive, changing in response to active infection of either the mother or infant (blog post on this topic

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Repost: Pumping experiences survey, pt1

Pumping experiences survey – Post 1 of the Series   First off, a giant THANK YOU to all the mothers who participated in the online survey. Your assistance was amazing! We started the pumping experiences survey to see how mothers would respond to differences in pump output, based on their normal pumping experiences. We had predicted that mothers who had dramatic changes in output in the experiment – either randomized to much more or much less than they typically produced – would have strong reactions to the images and the responses would tell us a lot about how women perceive their milk supply. The survey randomly assigned each mother to one of three images showing expressed breast milk– one photo showed 1 ounce of pumped milk, the second photo showed 6 ounces of milk, and the final photo showed 12+ ounces of milk. The volumes were classified as “low”, “intermediate”, and “high” volume. The photos created an experimental condition where

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